Venture Building in Pharma: How to Innovate Like a Startup

December 2025

Why are pharma companies increasingly looking to startup-style venture building?

Pharma and life sciences companies face pressure to innovate beyond molecules. The shift toward digital therapeutics, patient engagement platforms, AI-driven tools, and personalised care means they must operate more like software companies than traditional manufacturers.

But large enterprises aren’t built for rapid experimentation. Venture building gives pharma a way to adopt startup speed without abandoning rigour or compliance.

It creates small, empowered teams that can build and validate new digital products quickly — while leveraging the parent company’s scientific, regulatory, and distribution strengths.

What makes venture building different from innovation theatre?

Innovation theatre looks exciting but rarely produces market-ready products. Slide decks, brainstorms, hackathons, and pilots that never scale are common symptoms.

Venture building, by contrast, is structured to deliver:

  • Real ownership and accountability
  • Dedicated cross-functional teams
  • Clear value propositions
  • Defined evidence requirements
  • Strong product-market fit testing
  • A pathway to scale

It transforms innovation from a creative exercise into an operational capability.

What venture-building models work best for pharma?

1. Internal venture studios

Pharma creates small startup-style teams inside the organisation. These teams own product discovery, design, development, and early testing.

2. External venture studios

Pharma partners with specialist venture builders who provide product talent, UX expertise, and digital strategy, while the company provides domain expertise.

3. Co-creation partnerships

Pharma collaborates with startups to build new digital products together, sharing risk and speed.

4. Accelerator models

Pharma supports external startups through funding and resources, gaining insights and early rights to emerging technologies.

Each model balances speed, control, and risk differently — but all create a faster path to product.

What problems does venture building solve?

Venture building helps pharma overcome structural challenges:

  • Slow decision cycles
  • Fragmented digital capabilities
  • Siloed teams
  • Difficulty recruiting digital talent
  • Rigid development processes
  • Lack of user-centred design
  • Misalignment between science and software

By building small, multidisciplinary teams, companies move faster and design more user-friendly solutions.

Which capabilities must a venture team include?

Successful pharma venture teams blend:

  • Product strategy
  • UX and service design
  • Engineering
  • Clinical insight
  • Regulatory expertise
  • Market access knowledge
  • Data science (where relevant)

This cross-functional approach ensures ideas are viable, usable, feasible, and compliant.

How do venture teams validate ideas quickly?

1. Clear problem definition

Startups succeed because they obsess over real user problems. Venture teams must do the same.

2. Rapid prototyping

Lo-fi interfaces, service blueprints, and clickable prototypes help de-risk assumptions.

3. User testing with clinicians and patients

Not theoretical “personas” — but real end-users.

4. Clinical and regulatory feasibility assessment

A concept that can’t be approved or reimbursed is a non-starter.

5. Market sizing and commercial modelling

Startups must understand their buyers; venture teams should too.

6. Evidence-roadmapping

What studies and proof points are needed for launch, reimbursement, or adoption?

These steps prevent teams from investing years into unvalidated ideas.

What does “scale” look like in pharma venture building?

Once validated, ventures move into:

  • Technical hardening
  • Regulatory submissions
  • Market access strategy
  • Integration with enterprise systems
  • Launch planning
  • Country-by-country adaptation

Some ventures even spin out into standalone companies, allowing pharma to capture upside without absorbing the product fully into slow-moving structures.

Why does venture building matter now?

Digital therapeutics, AI-enabled care pathways, and real-world evidence products all require a blend of design, software, and clinical excellence. Pharma companies that master venture building will shape the next decade of digital health — and build competitive advantages in patient engagement and digital IP.

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